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November 20, 2006

Poor Reading Skills Raise Teen Suicide Risk

Teens who can't read well may also be at high risk for suicide, a new study warns. They're also more likely than other kids their age to drop out of school. Poor readers were three times more likely than typical readers to consider or attempt suicide and six times more likely to drop out of school. Source: http://www.adhdissues.com/ms/news/535821/main.html

Stronger Warnings for ADHD Stimulants

Adderall: FDA Issues Stronger Warnings for ADHD Stimulants

The FDA now requires the manufacturers of amphentamine-containing ADHD drugs (Adderall) to include a black box warning, which is found in the package insert, informing patients about the possibility of sudden death and serious cardiovascular problems associated with these drugs. Source: http://www.worstpills.org

November 01, 2006

New Pediatric ADHD Drug Has Potential for Less Abuse

An investigational d-amphetamine prodrug appears to be effective in treating pediatric attention deficit hyperactivity disorder with the goal of less abuse potential than amphetamines. All dose levels of lisdexamfetamine (NRP104) were significantly more effective than the placebo. The result of a phase III study was presented at the American Academy of Child and Adolescent Psychiatry meeting.

The study included 290 patients aged six to 12 with a primary diagnosis of ADHD. The participants were randomized to receive 30 mg, 50 mg, or 70 mg daily or placebo for four weeks followed by a 30 day observation period. Researchers concluded that those who received the drug were much improved than those who received the placebo.

Adverse events were consistent with what has been seen with other amphetamines. No serious adverse events were reported and most were mild or moderate in severity. The study was supported by New River Pharmaceuticals, which developed the drug, and Shire, which will market it. (Med Page)